Digestion and Absorption
Analytical deep dive — question counts, mark distribution, mastery curves, command-word breakdowns, and examiner narrative analysis.
3.3.3 (Digestion and Absorption) appeared in 4 of the 8 years between 2017 and 2024, contributing 5 questions and 13 marks across Papers 1, 2 and 3. KNOWLEDGE dominates the mark distribution at 76.9% of total marks. The accessibility–mastery gap sits at 41.7 percentage points (58.3% vs 16.7%) — most students reach partial credit, but full marks remain harder to secure. Mastery varied year-to-year, lowest in 2025 (15.0%) and highest in 2024 (17.5%).
| Year | Questions | Total marks | Mean accessibility | Mean mastery |
|---|---|---|---|---|
| 2017 | 0 | 0 | — COVID | — COVID |
| 2018 | 0 | 0 | — COVID | — COVID |
| 2019 | 0 | 0 | — COVID | — COVID |
| 2020 | 1 | 3 | — COVID | — COVID |
| 2021 | 1 | 2 | — COVID | — COVID |
| 2022 | 0 | 0 | — COVID | — COVID |
| 2023 | 0 | 0 | — COVID | — COVID |
| 2024 | 2 | 4 | 47.5% | 17.5% |
| Term | Times credited | Years | Notes |
|---|---|---|---|
| bile salts | 2 | 2020, 2024 | |
| fatty acids | 2 | 2020, 2025 | |
| diffusion | 2 | 2020, 2025 | |
| surface area | 2 | 2021, 2025 | |
| micelles | 2 | 2024, 2025 | |
| cell-surface membrane | 2 | 2024, 2025 |
| Term | Times credited | Years | Notes |
|---|---|---|---|
| facilitated diffusion (for fat absorption) | 1 | 2020 | |
| hairs | 1 | 2024 | |
| villi | 1 | 2024 | |
| membrane structures inside cells | 1 | 2024 | |
| increased surface area (alone) | 1 | 2024 | |
| cilia | 1 | 2024 | |
| emulsification produces micelles | 1 | 2024 | |
| micelles diffuse across membrane | 1 | 2024 | |
| co-transport with sodium | 1 | 2024 | |
| chylomicrons | 1 | 2024 | |
| emulsification causes hydrolysis | 1 | 2025 | |
| triglyceride formation | 1 | 2025 | |
| facilitated diffusion of micelles | 1 | 2025 |
- Emulsification described as causing lipid hydrolysis directly — emulsification breaks fat droplets into smaller droplets to increase surface area for lipase; the hydrolysis is carried out by lipase, not by bile salts; stating "emulsification breaks down lipids" omits lipase entirely and was penalised in 2025 (2025 P1 Q01.1)
- Micelles described as diffusing across cell membranes intact — micelles are transport structures that release fatty acids and monoglycerides at the membrane surface; the individual molecules then diffuse through the phospholipid bilayer; the micelle unit does not cross the membrane (2024 P1 Q02.3, 2025 P1 Q01.1)
- Microvilli confused with villi — microvilli are single-cell folds of the cell-surface membrane; villi are multicellular finger-like projections of the gut lining involving many cells; most students described multicellular structures when the question asked about microvilli (2024 P1 Q02.2)
- "Increased surface area" given as the structural description of microvilli — increased surface area is the function that results from microvilli; the structure is folds of the cell-surface membrane; the two are not interchangeable (2024 P1 Q02.2)
- Fatty acids and monoglycerides not named as the molecules that diffuse — "digested lipids" is insufficiently specific; the mark scheme requires fatty acids and/or monoglycerides to be named as the molecules released from micelles and absorbed across the membrane (2025 P1 Q01.1)
- Sodium co-transport invoked for vitamin A absorption — vitamin A is a lipid-soluble molecule that diffuses through the phospholipid bilayer; sodium ion co-transport is the mechanism for glucose and amino acid absorption and is not relevant to lipid-soluble vitamin uptake (2024 P1 Q02.3)
- Golgi processing and chylomicron production described after absorption — the question in 2024 asked how vitamin A is absorbed into ileum cells; many students continued into intracellular processing, Golgi modification, and chylomicron release, none of which answered what was asked; the absorption step is where marks sat (2024 P1 Q02.3)
The accessibility–mastery gap of 41.7 percentage points characterises this sub-section's difficulty profile. Most students reach partial credit; full marks remain harder to achieve. Within 3.3 (Organisms exchange substances with their environment), 3.3.3 ranks 1 of 4 sub-sections by mean mastery (1 = hardest). Mean mastery was lowest in 2025 (15.0%) and highest in 2024 (17.5%).